PhoPQ regulated genes that are differentially expressed in S. typhimurium as well as E. coli


Motif in S. typhimurium Motif in E. coli Description Number List
no no Indirectly PhoPQ regulated genes in S. typhimurium and E. coli 10 list
yes Indirectly PhoPQ regulated genes in S. typhimurium but directly PhoPQ regulated in E. coli 0 list
yes no Directly PhoPQ regulated genes in S. typhimurium but indirectly PhoPQ regulated in E. coli 1 list
yes Directly PhoPQ regulated genes in S. typhimurium and E. coli 2 list


 [
top] Indirectly PhoPQ regulated genes in S. typhimurium and E. coli
S. typhimuriumE. coli
OperonIDgeneexpressionfunctionOperonIDgeneexpressionfunction
2001gcvH+ STM3054 Ortholog of E. coli in glycine cleavage complex, carrier of aminomethyl moiety via covalently bound lipoyl cofactor (AAC75942.1); Blastp hit to AAC75942.1 (129 aa), 99% identity in aa 1 - 129 glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor1872gcvH0 b2904 100 pct identical to GCSH_ECOLI SW: P23884 in glycine cleavage complex, carrier of aminomethyl moiety via covalently bound lipoyl cofactor
gcvT0 STM3055 Ortholog of E. coli aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (AAC75943.1); Blastp hit to AAC75943.1 (364 aa), 94% identity in aa 1 - 364 glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependentgcvT0 STM3055 Ortholog of E. coli aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (AAC75943.1); Blastp hit to AAC75943.1 (364 aa), 94% identity in aa 1 - 364 glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent
1553STM2344+ Paralog of E. coli putative PTS system enzyme II A component (AAC77152.1); Blastp hit to AAC77152.1 (154 aa), 41% identity in aa 12 - 149 putative phosphotransferase system1889cmtB0 b2934 f147; 100 pct identical to PTYA_ECOLI SW: P32058; alternate name tolM; putative enzyme III of PEP- phosphotransferase system(PTS) PTS system, mannitol-specific enzyme II component, cryptic
   cmtA+b2933 f462; Residues 1-415 99 pct identical (1 gap) toPTYC_ECOLI SW: P32059 but C-termini differ due to vector contamination in the database entry; alternate name tolM PTS system, mannitol-specific enzyme II component, cryptic
2761malG+ STM4227 S. typhimurium maltose transport system permease protein MALG. (SW:MALG_SALTY) ABC superfamily (membrane), maltose transport protein2585malG+ b4032 f296; 100 pct identical to MALG_ECOLI SW: P07622; CG Site No. 530 part of maltose permease, inner membrane
malF0 STM4228 S. typhimurium maltose transport system permease protein MALF. (SW:MALF_SALTY) ABC superfamily (membrane), maltose transport protein Putative RBS for malG; RegulonDB:STMS1H004133malF0 STM4228 S. typhimurium maltose transport system permease protein MALF. (SW:MALF_SALTY) ABC superfamily (membrane), maltose transport protein Putative RBS for malG; RegulonDB:STMS1H004133
1590pgtE+ STM2395 S. typhimurium outer membrane protease E precursor. (SW:PGTE_SALTY) Phosphoglycerate transport: outer membrane protein E376ompT+ b0565 f317; 100 pct identical to OMPT_ECOLI SW: P09169 outer membrane protein 3b (a), protease VII
509galE0 STM0776 S. typhimurium UDP-glucose 4-epimerase. (SW:GALE_SALTY) UDP-galactose 4-epimerase Putative RBS for galT; RegulonDB:STMS1H001076 Putative binding site for GalR, RegulonDB: STMS1H000195501galE0 b0759 f338; 100 pct identical to GALE_ECOLI SW: P09147; alternate gene name galD UDP-galactose-4-epimerase
galK0 STM0774 S. typhimurium galactokinase. (SW:GAL1_SALTY) galactokinase Putative RBS for galM; RegulonDB:STMS1H001074galK0 STM0774 S. typhimurium galactokinase. (SW:GAL1_SALTY) galactokinase Putative RBS for galM; RegulonDB:STMS1H001074
galT+ STM0775 S. typhimurium galactose-1-phosphate uridylyltransferase. (SW:GAL7_SALTY) galactose-1-phosphate uridylyltransferase Putative RBS for galK; RegulonDB:STMS1H001075galT+ STM0775 S. typhimurium galactose-1-phosphate uridylyltransferase. (SW:GAL7_SALTY) galactose-1-phosphate uridylyltransferase Putative RBS for galK; RegulonDB:STMS1H001075
2143yraO+ STM3266 Ortholog of E. coli orf, hypothetical protein (AAC76183.1); Blastp hit to AAC76183.1 (196 aa), 98% identity in aa 3 - 196 putative phosphoheptose isomerase Putative RBS for yraP; RegulonDB:STMS1H0032932028yraO0 b3149 o196; 100 pct identical amino acid sequence and equal length to YRAO_ECOLI SW: P45466 orf, hypothetical protein
yraN0 STM3265 Ortholog of E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131 putative endonucleaseyraN0 STM3265 Ortholog of E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131 putative endonuclease
yraP+ STM3267 Ortholog of E. coli putative periplasmic protein (AAC76184.1); Blastp hit to AAC76184.1 (191 aa), 92% identity in aa 1 - 191 paral putative periplasmic proteinyraP+ STM3267 Ortholog of E. coli putative periplasmic protein (AAC76184.1); Blastp hit to AAC76184.1 (191 aa), 92% identity in aa 1 - 191 paral putative periplasmic protein
523bioF+ STM0795 Ortholog of E. coli 8-amino-7-oxononanoate synthase (AAC73863.1); Blastp hit to AAC73863.1 (384 aa), 80% identity in aa 1 - 384 7-keto-8-aminopelargonic acid synthetase Putative RBS for bioC; RegulonDB:STMS1H001097515bioF0 b0776 o384; 100 pct identical to BIOF_ECOLI SW: P12998 8-amino-7-oxononanoate synthase
bioC+ STM0796 Ortholog of E. coli biotin biosynthesis; reaction prior to pimeloyl CoA (AAC73864.1); Blastp hit to AAC73864.1 (251 aa), 70% identity in aa 1 - 251 biotin biosynthesis; reaction prior to pimeloyl CoA Putative RBS for bioD; RegulonDB:STMS1H001098bioC+ STM0796 Ortholog of E. coli biotin biosynthesis; reaction prior to pimeloyl CoA (AAC73864.1); Blastp hit to AAC73864.1 (251 aa), 70% identity in aa 1 - 251 biotin biosynthesis; reaction prior to pimeloyl CoA Putative RBS for bioD; RegulonDB:STMS1H001098
bioB+ STM0794 Ortholog of E. coli biotin synthesis, sulfur insertion? (AAC73862.1); Blastp hit to AAC73862.1 (346 aa), 94% identity in aa 1 - 346 biotin synthetase Putative RBS for bioF; RegulonDB:STMS1H001096bioB+ STM0794 Ortholog of E. coli biotin synthesis, sulfur insertion? (AAC73862.1); Blastp hit to AAC73862.1 (346 aa), 94% identity in aa 1 - 346 biotin synthetase Putative RBS for bioF; RegulonDB:STMS1H001096
bioD+ STM0797 Ortholog of E. coli dethiobiotin synthetase (AAC73865.1); Blastp hit to AAC73865.1 (225 aa), 74% identity in aa 1 - 225 dethiobiotin synthetasebioD+ STM0797 Ortholog of E. coli dethiobiotin synthetase (AAC73865.1); Blastp hit to AAC73865.1 (225 aa), 74% identity in aa 1 - 225 dethiobiotin synthetase
566dacC+ STM0863 Ortholog of E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400 D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6a555dacC+ b0839 o400; 99 pct identical to DACC_ECOLI SW: P08506 D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6
2532atpH0 STM3868 Ortholog of E. coli membrane-bound ATP synthase, F1 sector, delta-subunit (AAC76758.1); Blastp hit to AAC76758.1 (177 aa), 94% identity in aa 1 - 177 membrane-bound ATP synthase, F1 sector, delta-subunit2385atpH0 b3735 f177; 100 pct identical to ATPD_ECOLI SW: P00831; alternate gene names uncH, papE; CG Site No. 26 membrane-bound ATP synthase, F1 sector, delta-subunit
atpA+ STM3867 Ortholog of E. coli membrane-bound ATP synthase, F1 sector, alpha-subunit (AAC76757.1); Blastp hit to AAC76757.1 (513 aa), 98% identity in aa 1 - 513 membrane-bound ATP synthase, F1 sector, alpha-subunitatpA+ STM3867 Ortholog of E. coli membrane-bound ATP synthase, F1 sector, alpha-subunit (AAC76757.1); Blastp hit to AAC76757.1 (513 aa), 98% identity in aa 1 - 513 membrane-bound ATP synthase, F1 sector, alpha-subunit
atpF0 STM3869 Ortholog of E. coli membrane-bound ATP synthase, F0 sector, subunit b (AAC76759.1); Blastp hit to AAC76759.1 (156 aa), 96% identity in aa 1 - 156 membrane-bound ATP synthase, F0 sector, subunit b Putative RBS for atpH; RegulonDB:STMS1H003824atpF0 STM3869 Ortholog of E. coli membrane-bound ATP synthase, F0 sector, subunit b (AAC76759.1); Blastp hit to AAC76759.1 (156 aa), 96% identity in aa 1 - 156 membrane-bound ATP synthase, F0 sector, subunit b Putative RBS for atpH; RegulonDB:STMS1H003824
1642talA+ STM2473 Ortholog of E. coli transaldolase A (AAC75517.1); Blastp hit to AAC75517.1 (316 aa), 89% identity in aa 1 - 316 transaldolase A1890tktA+ b2935 f663; differs from earlier version (TKT1_ECOLI SW:P27302); CG Site No. 103 transketolase 1 isozyme
tktB+ STM2474 Ortholog of E. coli transketolase 2 isozyme (AAC75518.1); Blastp hit to AAC75518.1 (667 aa), 92% identity in aa 1 - 666 transketolase 2, isozymetktB0b2465 o667; 100 pct identical to TKT2_ECOLI SW: P33570 transketolase 2 isozyme

 [
top] Indirectly PhoPQ regulated genes in S. typhimurium but directly PhoPQ regulated in E. coli
S. typhimuriumE. coli
OperonIDgeneexpressionfunctionOperonIDgeneexpressionfunction

 [
top] Directly PhoPQ regulated genes in S. typhimurium but indirectly PhoPQ regulated in E. coli
S. typhimuriumE. coli
OperonIDgeneexpressionfunctionOperonIDgeneexpressionfunction
417pagP+ STM0628 S. typhimurium PagP (gi|3789781) PhoPQ-activated gene416crcA+ b0622 o186; 100 pct identical to GB: ECOGICA_1 ACCESSION: L29054; 100 pct. identical to 156 amino acids of YBEG_ECOLI SW: P37001 but contains 30 additional N-terminal residues orf, hypothetical protein

 [
top] Directly PhoPQ regulated genes in S. typhimurium and E. coli
S. typhimuriumE. coli
OperonIDgeneexpressionfunctionOperonIDgeneexpressionfunction
964slyB+ STM1445 S. typhimurium outer membrane lipoprotein SLYB precursor. (SW:SLYB_SALTY) putative outer membrane lipoprotein1083slyB+ b1641 o155; 75 pct identical amino acid sequence and equal length to PCP_YEREN SW: P31484 putative outer membrane protein
813phoQ0 STM1230 S. typhimurium virulence sensor protein PHOQ. (SW:PHOQ_SALTY) sensory kinase protein in two-component regulatory system with PhoP, ligand is Mg+737phoQ+ b1129 f486; 99 pct identical to PHOQ_ECOLI SW: P23837 sensor protein PhoQ
phoP+ STM1231 S. typhimurium virulence transcriptional regulatory protein PHOP. (SW:PHOP_SALTY) response regulator in two-component regulatory system with PhoQ, transcribes genes expressed under low Mg+ concentration (OmpR family)phoP+ STM1231 S. typhimurium virulence transcriptional regulatory protein PHOP. (SW:PHOP_SALTY) response regulator in two-component regulatory system with PhoQ, transcribes genes expressed under low Mg+ concentration (OmpR family)