A data integration framework to reveal condition dependency of complex regulons in Escherichia coli
DISTILLER (Data Integration System To Identify Links in Expression Regulation) searches for transcriptional modules by combining expression data with information on the direct interaction between a regulator and its corresponding target genes. The algorithm has been described and validated in the following papers:
1. Lemmens K, De Bie T, Dhollander T, De Keersmaecker SC, Thijs IM, Schoofs G, De Weerdt A, De Moor B, Vanderleyden J, Collado-Vides J, Engelen K, Marchal K. "DISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli". Genome Biology , 10:R27 doi:10.1186/gb-2009-10-3-r27 (2009).
DISTILLER is freely available for ACADEMIC USE ONLY under the license. To download the software, registration is required. For commercial usage, please contact us.
kathleen.marchal<at>biw.kuleuven.be
Software Contributors: Tijl De Bie, Karen Lemmens, Hong Sun, Qiang Fu, Riet De Smet, Kristof Engelen, Kathleen Marhcal.