Module 70

Number of motifs
Number of conditions
Number of seed genes
Number of extended seed genes
Correlation extended seed
No. (putative) regulators in module
=
=
=
=
=
=
1
60
6
22
0.89842
0

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Additional motif analysis

Motif information

MotifMotif logoModule motif logo
Fur:
negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer




Gene information

GeneSeed/Extended SeedDescriptionDirect interaction (RegulonDB)Indirect interaction (RegulonDB)Motif instance
b3006 (exbB)Seed ExbB protein; uptake of enterochelin; tonB-dependent uptake of B colicinsFur

-

ATGAGAACGACTATCA

b2673 (nrdH)Seed glutaredoxin-like proteinFur

-

ATGCGCATTACTATTT

b2392 (mntH)Seed MntH manganese ion NRAMP transporter  

-

TTGATAATCATTCTCG

b4367 (fhuF)Seed acts in reduction of ferrioxamine B ironFur

-

ATGATAATTTTTATCA

b1684 (sufA)Seed Fe-S cluster assembly proteinFur

-

CTGATAATCATTATCA

b0755 (gpmA)Seed phosphoglyceromutase 1 monomerFur

-

ATGAGAATTATTATCA

b4293 (fecI)Extension RNA polymerase, sigma 19 factorFur

-

ATGATAACCATTCTCA

b1452 (yncE)Extension conserved protein  



ATGATTACGCTTAGCG

b1679 (sufE)Extension sulfur acceptor that activates SufS cysteine desulfurase  

-

  

b1252 (tonB)Extension TonB protein; energy transducer; uptake of iron, cyanocobalimin; sensitivity to phages, colicinsFur

+-

ATGATTGCTATTTGCA

b0592 (fepB)Extension FepBFur

-

ATGAGAAGCATTATTG

b3005 (exbD)Extension ExbD uptake of enterochelin; tonB-dependent uptake of B colicinsFur

-

ATGGCAATGCATCTTA

b3337 (bfd)Extension bacterioferritin-associated ferredoxin  



ATAAGAACTATTTTCA

b2674 (nrdI)Extension conserved protein that may stimulate ribonucleotide reductase  

-

  

b1683 (sufB)Extension component of SufB-SufC-SufD cysteine desulfurase (SufS) activator complex  

-

  

b1681 (sufD)Extension component of SufB-SufC-SufD cysteine desulfurase (SufS) activator complex  

-

  

b2675 (nrdE)Extension NrdE  

-

ACGCAAAGCGATATCG

b0584 (fepA)Extension FepA, outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and DFur

-

TTGATAACTATTTGCA

b1680 (sufS)Extension L-selenocysteine lyase (and L-cysteine desulfurase) monomer  

-

  

b1682 (sufC)Extension component of SufBCD complex  

-

  

b2676 (nrdF)Extension NrdF  

-

  

b0468 (ybaN)Extension conserved inner membrane protein  



ATGATAATTGTTATGC