Number of conditions
Number of seed genes
Number of extended seed genes
Correlation extended seed
No. (putative) regulators in module
=
=
=
=
=
51
10
33
0.86864
1
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![[View full size image]](./ExpressionProfiles/ExpressionProfile_seed_module_5.png){kind=link}
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| Number of motifs Number of conditions Number of seed genes Number of extended seed genes Correlation extended seed No. (putative) regulators in module | = = = = = = | 1 51 10 33 0.86864 1 | [View full size image] | [View full size image] |
| Motif | Motif logo | Module motif logo |
|---|---|---|
| Fur: negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer |  |  |
| Gene | Seed/Extended Seed | Description | Direct interaction (RegulonDB) | Indirect interaction (RegulonDB) | Motif instance |
|---|---|---|---|---|---|
| b4293 (fecI) | Seed | RNA polymerase, sigma 19 factor | Fur | - | ATGATAACCATTCTCA |
| b0593 (entC) | Seed | isochorismate synthase 1 | Fur | - | ATGATAATCATTATTA |
| b1102 (fhuE) | Seed | outer membrane receptor for ferric iron uptake | Fur | - | GGGATAATCAATATCA |
| b2673 (nrdH) | Seed | glutaredoxin-like protein | Fur | - | ATGCGCATTACTATTT |
| b0592 (fepB) | Seed | FepB | Fur | - | ATGAGAAGCATTATTG |
| b0585 (fes) | Seed | enterochelin esterase | Fur | - | ATGCAAATAGTTATCA |
| b0591 (entS) | Seed | EntS MFS transporter | Fur | +- | ATGAAATTAATTATCG |
| b4291 (fecA) | Seed | outer membrane receptor; citrate-dependent iron transport, outer membrane receptor | Fur | - | AGGAAAATAATTCTTA |
| b0584 (fepA) | Seed | FepA, outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D | Fur | - | TTGATAACTATTTGCA |
| b2155 (cirA) | Seed | outer membrane receptor for iron-regulated colicin I receptor; porin; requires tonB gene product | Fur | - | TTGATAATTGTTATCG |
| b0594 (entE) | Extension | EntE | | - | |
| b3006 (exbB) | Extension | ExbB protein; uptake of enterochelin; tonB-dependent uptake of B colicins | Fur | - | ATGAGAACGACTATCA |
| b3070 (yqjH) | Extension | hypothetical protein | | TTAACAATCATTATCA | |
| b1452 (yncE) | Extension | conserved protein | | ATGATTACGCTTAGCG | |
| b0583 (entD) | Extension | | - | | |
| b0805 (fiu) | Extension | putative outer membrane receptor for iron transport | Fur | - | ATCAAAATTATTATCA |
| b1252 (tonB) | Extension | TonB protein; energy transducer; uptake of iron, cyanocobalimin; sensitivity to phages, colicins | Fur | +- | ATGATTGCTATTTGCA |
| b3005 (exbD) | Extension | ExbD uptake of enterochelin; tonB-dependent uptake of B colicins | Fur | - | ATGGCAATGCATCTTA |
| b3337 (bfd) | Extension | bacterioferritin-associated ferredoxin | | ATAAGAACTATTTTCA | |
| b0150 (fhuA) | Extension | FhuA outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 | | - | ATAATAATCATTCTCG |
| b0586 (entF) | Extension | apo-serine activating enzyme | | - | |
| b0597 (ybdB) | Extension | esterase | | - | |
| b4290 (fecB) | Extension | FecB | | - | |
| b2674 (nrdI) | Extension | conserved protein that may stimulate ribonucleotide reductase | | - | |
| b1705 (ydiE) | Extension | conserved protein | | GTTATATCAATTATTA | |
| b2675 (nrdE) | Extension | NrdE | | - | ACGCAAAGCGATATCG |
| b4367 (fhuF) | Extension | acts in reduction of ferrioxamine B iron | Fur | - | ATGATAATTTTTATCA |
| b1684 (sufA) | Extension | Fe-S cluster assembly protein | Fur | - | CTGATAATCATTATCA |
| b4292 (fecR) | Extension | regulator for fec operon, periplasmic | | - | |
| b0596 (entA) | Extension | EntA | | - | |
| b0595 (entB) | Extension | EntB | | - | |
| b1682 (sufC) | Extension | component of SufBCD complex | | - | |
| b2676 (nrdF) | Extension | NrdF | | - | |
![[View full size image]](./ExpressionProfiles/ExpressionProfile_extend_module_5.png){kind=link}