Number of conditions
Number of seed genes
Number of extended seed genes
Correlation extended seed
No. (putative) regulators in module
=
=
=
=
=
77
6
16
0.88771
0
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![[View full size image]](./ExpressionProfiles/ExpressionProfile_seed_module_21.png){kind=link}
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| Number of motifs Number of conditions Number of seed genes Number of extended seed genes Correlation extended seed No. (putative) regulators in module | = = = = = = | 1 77 6 16 0.88771 0 | [View full size image] | [View full size image] |
| Motif | Motif logo | Module motif logo |
|---|---|---|
| Fur: negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer |  |  |
| Gene | Seed/Extended Seed | Description | Direct interaction (RegulonDB) | Indirect interaction (RegulonDB) | Motif instance |
|---|---|---|---|---|---|
| b1451 (yncD) | Seed | probable TonB-dependent receptor | | ATGGTAATCATTATTT | |
| b1252 (tonB) | Seed | TonB protein; energy transducer; uptake of iron, cyanocobalimin; sensitivity to phages, colicins | Fur | +- | ATGATTGCTATTTGCA |
| b3005 (exbD) | Seed | ExbD uptake of enterochelin; tonB-dependent uptake of B colicins | Fur | - | ATGGCAATGCATCTTA |
| b0150 (fhuA) | Seed | FhuA outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 | | - | ATAATAATCATTCTCG |
| b1018 (ycdO) | Seed | conserved protein | | ATGATAATCGCTATCA | |
| b4367 (fhuF) | Seed | acts in reduction of ferrioxamine B iron | Fur | - | ATGATAATTTTTATCA |
| b4293 (fecI) | Extension | RNA polymerase, sigma 19 factor | Fur | - | ATGATAACCATTCTCA |
| b3006 (exbB) | Extension | ExbB protein; uptake of enterochelin; tonB-dependent uptake of B colicins | Fur | - | ATGAGAACGACTATCA |
| b3070 (yqjH) | Extension | hypothetical protein | | TTAACAATCATTATCA | |
| b1452 (yncE) | Extension | conserved protein | | ATGATTACGCTTAGCG | |
| b0593 (entC) | Extension | isochorismate synthase 1 | Fur | - | ATGATAATCATTATTA |
| b3908 (sodA) | Extension | SodA | Fur | - | TTGATAATCATTTTCA |
| b0591 (entS) | Extension | EntS MFS transporter | Fur | +- | ATGAAATTAATTATCG |
| b2211 (yojI) | Extension | YojI | | ATAAGAATTATTATTG | |
| b2155 (cirA) | Extension | outer membrane receptor for iron-regulated colicin I receptor; porin; requires tonB gene product | Fur | - | TTGATAATTGTTATCG |
| b0468 (ybaN) | Extension | conserved inner membrane protein | | ATGATAATTGTTATGC |
![[View full size image]](./ExpressionProfiles/ExpressionProfile_extend_module_21.png){kind=link}